Chloroquine dosing for lupus retina

Discussion in 'Canada Drugs' started by guestg, 24-Feb-2020.

  1. SpiritXP New Member

    Chloroquine dosing for lupus retina


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

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    Chloroquine CQ is used to prevent and treat malaria and amebiasis, while hydroxychloroquine HCQ, a less toxic metabolite of chloroquine, is used to treat rheumatic diseases such as systemic lupus erythematosus SLE, rheumatoid arthritis RA, juvenile idiopathic arthritis JIA and Sjogren's syndrome. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. At first, 10 milligram mg per kilogram kg of body weight. Then, 5 mg per kg of body weight taken 6 hours, 24 hours, and 36 hours after the first dose. For treatment of liver infection caused by protozoa Adults—1000 milligrams mg once a day, taken for 2 days.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Chloroquine dosing for lupus retina

    Chloroquine and Hydroxychloroquine Toxicity Practice., Drug spotlight on hydroxychloroquine Lupus Foundation of.

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  7. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects.

    • Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus..
    • Chloroquine Oral Route Proper Use - Mayo Clinic.
    • Chloroquine Nivaquine, Resochin Healing Is Divine..

    No patient was found to have retinopathy. No correlation could be found between indices of visual field function and total drug usage, average daily dose, dosage in mg/kg body weight or duration of treatment. Retinopathy is unlikely to occur at dosages of hydroxychloroquine of less than 6.5 mg/kg body weight with under 10 years of treatment. Apr 20, 2011 Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ.

     
  8. Tchokurov Moderator

    Plaquenil (Hydroxychloroquine) is used for a number of conditions. Buy Plaquenil Hydroxychloroquine Online Canada Pharmacy Depot Buy Plaquenil online in USA - Proven Plaquenil no RX Buy Plaquenil Online From Canadian PricePro Pharmacy
     
  9. Skytext Guest

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. CHLOROQUINE PHOSPHATE, USP - Sanofi Chloroquine West-ward Pharmaceutical Corp FDA Package. CDC - Malaria - Glossary
     
  10. freak.zp New Member

    Inflammatory Osteoarthritis And Plaquenil Nov 28, 2010 Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells.

    Plaquenil - FDA prescribing information, side effects and uses
     
  11. tip Guest

    Plaquenil and Imuran drug interactions - eHealthMe Drug interactions are reported among people who take Plaquenil and Imuran together. This study is created by eHealthMe based on reports of 1,851 people who take Plaquenil and Imuran from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports.

    Plaquenil & Gabapentin - Lupus and Fibromyalgia" Lupus.