One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Ic50 hydroxychloroquine What is hydroxychloroquine sulfate 200 Autophagy inhibitors hydroxychloroquine Plaquenil hives Aug 01, 2009 After seeing MANY professionals including a neurologist, a retinal specialist, neuro-ophthalmologist, and undergoing MANY different tests, she was diagnosed with Plaquenil toxicity. She does have field of vision loss, mostly on things that are close up. She took Plaquenil for almost five years before having any symptoms. Plaquenil induced retinal toxicity is reversible if detected early and plaquenil dosage altered or the medication discontinued. Even suspicious early plaquenil toxicity warrants communication with the patient’s treating physician, and meaningful coordination of care would include a report even if the findings are normal. Aug 30, 2011 Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Signs of plaquenil toxicity Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS Plaquenil ra forum Dec 04, 2014 Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions. Hydroxychloroquine retinopathy A review of imaging. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Rx Side Effects New Plaquenil Guidelines and More - American.. The characteristics of patients which may increase of developing toxicity symptoms while taking Plaquenil include an age of more than 60 years old, having renal or hepatic insufficiency or any existing macular degeneration and retinal disease 1. So after taking plaquenil for 10 years for SLE and Sjogrens my latest annual eye exam shows signs of retinal toxicity. Plaquenil has worked for the most part to keep things in check. Has anyone had to stop plaquenil and if so what was the next line of treatment you were offered? - Thanks Again, VeeJ. I will have a look Nov 20, 2019 Plaquenil toxicity refers to a retinal condition caused by the use of the drug Plaquenil hydroxychloroquine. Plaquenil is most commonly prescribed to patients with rheumatoid arthritis, systemic lupus, and Sjögren’s syndrome, but it is also sometimes used in dermatological contexts due to its anti-inflammatory properties.