Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Plaquenil retinal screening guidelines afters stopping Chloroquine autophagy inhibitor Plaquenil lucite polymorphe A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Dr. Marmor, who chaired the Academy’s screening guidelines committee, said the goal in Plaquenil screening is to catch changes at a very early stage when there’s just a minimal amount of loss of vision. “Then, when you stop the drug, the damage won’t progress enough to cross the fovea and affect reading vision.” If you’re having issues with Plaquenil, have your doctor draw labs and watch the levels of concentration in your blood. ^ This is not common. Keep an eye on side effects you might be having. One of the reasons I’m posting is that, for someone with Lupus, she was very healthy. We used to joke that she had “Lupus light”. Flares were. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Plaquenil cross eyes Do either hydroxychol/Plaquenil put you at risk for., Rx Side Effects New Plaquenil Guidelines and More. How does azithoprine work with plaquenil fir lupusPlaquenil reportPlaquenil therapy icd 10 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Call your doctor at once if you have Plaquenil Uses, Dosage & Side Effects -. Plaquenil, a warning. lupus. Vision Coverage - Blue Cross and Blue Shield of Illinois. Here is an excerpt from 28 Lupus Secrets written by Dr. Donald Thomas, author of the Lupus Encyclopedia All patients should be on an antimalarial. Preventing eye side effects from Plaquenil American Academy of Ophthalmology Recommended dosing for women ≥ 5’7” = 400 mg a day; 5 ½” – 5’6 ½ “ = 300 mg a day; Less than 5 ½” = 200 mg a day Does Patient with Lupus Have Plaquenil Retinopathy. as it does not cross the blood-retinal barrier as chloroquine does.3,4. Perform a complete eye examination, including a dilated fundus exam. Do this within four weeks of the commencement of Plaquenil therapy, although it may be safely delayed for up to six months, as it takes this. Taking hydroxychloroquine for more than five years may develop retinopathy that can be detected with specialised tests. The risk is much higher in patients who have been taking the drug for 20 years or more. In these patients between 20 and 50 out of 100 will develop retinopathy. Cross-section of the eye Lens Cornea Macula Optic nerve Retina.