One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. Fortunately, very few prescription drugs have any known detrimental effects for people with AMD. Is hydroxychloroquine hepatotic Hydroxychloroquine remission rheumatoid arthritis Anyway I was diagnosed with dry macular degeneration 7 years ago. A recent exam showed it has worsened. I have also seen 3 rheumatologists, and 2 of them say I should take Plaquenil and the risk of damage to my macula is not big enough to not take the Plaquenil. Patients often ask if their medications affect the risk of vision loss from age-related macular degeneration AMD. One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect. A list of medications to use with caution if you have macular degeneration. The AMDF is a 501c3 non-profit, publicly supported organization. Contributions are tax deductible to the extent allowed by law. Doctors often put patients with certain potentially life-threatening cardiovascular conditions on this blood thinner. Warfarin (Coumadin®), which is an anticoagulant blood thinner, is one exception. Macular degeneration caused by plaquenil Retinal Imaging Purpose, Procedure, Risks, Resutls, Prescription Medications That Can Affect Age-Related. Hydroxychloroquine sulfate indicationsIs plaquenil a mitochondrial toxinCan plaquenil cause a positive nicotine urine testHydroxychloroquine tramadol interactionCan i take ibuprofen with hydroxychloroquine This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. Hydroxychloroquine-Induced Retinal Toxicity - American Academy of.. Medication Cautions in Macular Degeneration - AMDF. Can Plaquenil cause a macular pucker? - American Academy.. Or is any of the treatments used known to cause it? I have had a large number of drusen in my retina for about 10 year. The other day when I was at the opthamologist, for my visual field test for plaquenil, the assistant said I needed to be dilated because "having macular degeneration means thatyou need to be dialted every 6 months" I replied. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Sep 15, 2014 Fundus autofluorescence FAF indicates marked changes of macular toxicity in the mild and severe cases, represented by the central mottled hypo autofluorescence with surrounding rim of hyper autofluorescence, due to the retinal pigment epithelium RPE loss. FAF is a sensitive indicator of the RPE degeneration caused by the toxic progression.