Chloroquine retinopathy ppt

Discussion in 'Canadian Pharmacy Online' started by vezunchikl, 17-Mar-2020.

  1. varnak XenForo Moderator

    Chloroquine retinopathy ppt


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Chloroquine and Hydroxychloroquine. Chloroquine and its derivative, hydroxychloroquine sulfate, which have been useful in treating malaria and in larger doses, collagen-vascular disease, cause a cumulative dose-related pigmentary retinopathy. Hydroxychloroquine and chloroquine work in a similar way as antimalarial medication with different therapeutic and toxic doses and produce a similar pattern of retinopathy. HCQ appears to be considerably less toxic to the retina than CQ, possibly because chloroquine passes the blood – retinal barrier easier 10. Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Chloroquine retinopathy ppt

    Retinopathy PowerPoint PPT Presentations - PowerShow, Retinal toxicity associated with chronic exposure to hydroxychloroquine.

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  4. Objective To report the detailed clinical findings of patients with retinal toxicity that developed secondary to the use of hydroxychloroquine sulfate n = 13, chloroquine phosphate n = 2, or a combination of the agents n = 1.

    • Retinal Toxicity Associated With Hydroxychloroquine and..
    • Effects of chloroquine on viral infections an old drug..
    • Ocular side effects of systemic drugs.

    Most cases of chloroquine retinopathy have developed when a higher than currently recommended 3 mg/kg/day using lean body weight dose was used. 21 A daily dose exceeding 250 mg with a total cumulative dose between 100 and 300 g is customarily needed to produce toxicity. 22 One study showed a 19% incidence of chloroquine retinopathy in. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. The incidence of HCQ retinopathy is very low. In fact, HCQ is estimated at having a 0.5% incidence of retinal toxicity after 5 years of therapy. 5, 6 Retinal toxicity secondary to HCQ is irreversible and can continue to progress following cessation of therapy. 7 Prompt screening and serial monitoring.

     
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    These sudden, involuntary muscle contractions are common and usually harmless, but they can be excruciatingly painful. Causes of Leg Cramps and How to Stop Them Will you have Muscle cramps with Hydroxychloroquine sulfate. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  6. Polinurus Guest

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Plaquenil and pregnancy Hi there! I. - Hughes Syndrome Hydroxychloroquine Use in Lupus Patients during Pregnancy. Ask the Expert Plaquenil and Sjögren’s
     
  7. turbuleto XenForo Moderator

    Chloroquine Aralen - Side Effects, Dosage, Interactions. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.

    Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  8. snowball New Member

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