He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Echocardiography revealed a left ventricular ejection fraction of 25%, with diffuse hypokinesis. Chloroquin andgranuloma annulare Can you have withdrawals from hydroxychloroquine What percent of people on plaquenil have eye problems There is no Heart failure reported by people who take Plaquenil yet. This review analyzes which people have Heart failure with Plaquenil. It is created by eHealthMe based on reports from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Heart problems like heart failure and a certain abnormal heartbeat prolonged QT interval have happened with Plaquenil hydroxychloroquine. Sometimes, these heart problems have been deadly. Sometimes, these heart problems have been deadly. We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. The differential diagnosis for new onset non-ischemic cardiomyopathy in this patient included inflammatory cardiomyopathy, viral myocarditis, sarcoidosis, amyloidosis, hemochromatosis, Fabry's disease and HCQ toxicity. Coronary angiography demonstrated non-obstructive coronary disease. Treatment was initiated with guideline directed medical therapy, and patient clinically improved. Plaquenil and heart issues Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Indications, Side Effects, Warnings - Treatment of chloroquine resistant falciparum malariaHydroxychloroquine classificationDoes plaquenil treat sclerodermaRetinal toxicity dosage hydroxychloroquineHydroxychloroquin safety Sep 13, 2017 We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. Hydroxychloroquine-induced cardiomyopathy and heart failure.. Hydroxychloroquine-induced cardiomyopathy and heart failure in twins. Hydroxychloroquine prevents congenital heart block.. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Though serious heart muscle disease is not commonly caused by lupus, heart failure can occur if your heart does not have the strength to pump enough blood to the different tissues and organs. Endocarditis. The endocardium is the tissue that lines the inner walls of your heart and the valves that separate the heart’s different chambers. Some people may develop eye problems, so you’ll have to get your eyes checked often. Depending on what you're being treated for, it can take up to 6 months for the full benefits of Plaquenil hydroxychloroquine. Many people have nausea, stomach cramps, and diarrhea when they first start taking Plaquenil hydroxychloroquine.