One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil drug rash Chloroquine how to say Sep 13, 2019 If allowed to develop, there may be a risk of progression even after treatment withdrawal. -Patients with retinal changes may be asymptomatic initially, or may have scotomatous vision with paracentral, pericentral ring types, temporal scotomas, and abnormal color vision. What next if plaquenil doesn't work? Support Forums. I know it is scary but anything to stop the pain and misfunction of not being able to use my hands or move my knees or not have my ankles cave out and fall. switched to the cymbalta, perhaps the combination of it and 400 mg of plaquenil will work for me. It seemed to help the swelling. Early detection of the maculopathy is of critical importance to discontinue Plaquenil in order to stop or slow retinal damage. Unfortunately, clinically evident early structural changes can be subtle and usually preceded by abnormalities in functional tests such as visual field examination. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Swelling after stopping plaquenil Long-Term Side Effects of Plaquenil for Rheumatoid., What next if plaquenil doesn't work? - Rash caused by plaquenil As some of you know I started on Plaquenil 6 weeks ago. After two weeks I stopped it because of liver pain, and we found out I had raised liver enzymes. I stayed off it for two weeks until I could contact my rheumatologist who was on holiday My rheumatologist did not think think the Plaquenil w. Coming Off Plaquenil questions - Sclero Forums MAIN.. The Risk of Retinal Toxicity with Plaquenil - Sjogren's. Ask the Expert Plaquenil and Sjögren’s. After about 4 day of being off Plaquenil I quickly realized that it in deed was helping. I was at work and at the end of my day I proceeded to walk to my car and could barley raise my legs to walk. I legs felt so heavy, the fatigue was at an all time high and the joint and muscle pain was unbearable. Swollen feet and ankles in elderly lady Eyes pain while on Plaquenil Swollen lymph nodes and rash Side effects of Plaquenil Plaquenil side Effcts Red/Purple Painfully Swollen Feet & Legs Dr.'s can't figure it out. What is plaquenil? Swollen lumps in feet / swollen hands and knuckles the next itchy rash all over body, bumps, swelling of. I had been taking plaquenil since April for my lupus and sjogrens. It was working really well and just recently my rheumy told that I was in remission. I felt great. Then I had an allergic reaction to the plaquenil - a rash all over my body, neck, arms and legs. I stopped taking it 1 week ago.