It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Is hydroxychloroquine used for osteoarthritis Plaquenil causing low blood sugar Chloroquine help with payment for prescriptions Quinacrine Atabrine Quinacrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the Plaquenil on its own is not adequately managing symptoms. Only a compounding pharmacist can dispense Quinacrine as tablets are. Antimalarial agents were first used for lupus in 1894 when Payne treated a case of discoid lupus with quinine. It was not until 1951 that Page reported the benefits of quinacrine for lupus. The use of hydroxychloroquine for the cutaneous manifestations of DM were first described by Woo et al in 1984. I wonder if the commencement of the skin rashes and itching is related in some way to this decreased effectiveness of the medication too. So far from the other posts it may seems that Plaquenil may be somehow associated with skin rash that looks like small hives and patchy itchiness. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil for skin rash Plaquenil Side Effects Common, Severe, Long, Adverse Cutaneous Reactions to Hydroxychloroquine Are More. Chloroquine plaquenil Yes. Hair bleaching, hair loss, skin pigmentation, rash and itching are recognized skin adverse reactions of plaquenil hydroxychloroquine. These reactions tend to be worse if a patient is taking other medications that have similar skin toxicity. Please consult a dermatologist to ensure skin lesions are not psoriatic because Plaquenil hydroxychloroquine use needs special precautions in. Plaquenil hydroxychloroquine 200mg is it. Terrible Itching on Plaquenil---PLEASE HELP.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. I had a skin rash from plaquenil hydroxychloroquine. I was put on a 21 day taper of prednisone. How long before the prednisone increases my odds of catching viruses? Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.