Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine resistance countries Hydroxychloroquine with or without food Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Can I take zantac while taking methotrexate and plaquenil? Asked by margmac Updated 13 January 2015 Topics plaquenil, zantac, rheumatoid arthritis, methotrexate, antacid, stomach, contraindication Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine and ranitidine Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Plaquenil Hydroxychloroquine side effects skin rash I take one batch of tablets AM - hydroxychloroquine, MMF, mepacrine, anti-histamine in the moring. Lunch time - ranitidine I guess if you take this within 2 hours of other meds, that your medications wont be properly absorbed? Before bed - hydroxychloroquine, MMF, different anti-histamine and amitriptyline. Hope that helps. Wendy x Hydroxychloroquine I take Hydroxychloroquine 20. - LUPUS UK. Can I take zantac while taking methotrexate and plaquenil?. Hydroxychloroquine sulfate and Ranitidine hydrochloride drug.. Does anyone know how ranitidine/otc zantac is supposed to help lupus? I've been taking it for a few years. I recently ran out for a few days but couldn't really tell any difference. I take one a day and started back yesterday. Thanks. Nov 09, 2018 Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. The study is based on hydroxychloroquine sulfate and ranitidine hydrochloride the active ingredients of Plaquenil and Ranitidine hydrochloride, respectively, and Plaquenil and Ranitidine hydrochloride the brand names. Other drugs that have the same active ingredients e.g. generic drugs are not considered.