Now a paper published January 17 in the journal describes a new drug combination that has stabilized Rosendahl's disease and increased both the quantity and quality of her life: Adding the anti-malaria drug chloroquine to her treatment stopped an essential process that Rosendahl's cancer cells had been using to resist therapy, re-sensitizing her cancer to the targeted treatment that had previously stopped working. Along with Rosendahl, two other brain cancer patients were treated with the combination and both showed similar, dramatic improvement. Plaquenil treatment for vasculitis Shortness of breath related to plaquenil Plaquenil discount coupons Jan 20, 2017 The anti-malaria drug chloroquine has now been used as a last resort on three brain cancer patients, and in each case, it seems to have overcome the cancer's resistance to traditional treatments. Chloroquine appears to break down the defences that tumours develop in response to cancer-fighting drugs by effectively 'resetting' their vulnerability to treatment. The anti-malaria drug chloroquine has now been used as a last resort on three brain cancer patients, and in each case, it seems to have overcome the cancer's resistance to traditional treatments. Chloroquine appears to break down the defences that tumours develop in response to cancer-fighting drugs by effectively 'resetting' their vulnerability to treatment. Jan 17, 2017 The drug is known as chloroquine, and although traditionally an off-label malaria drug, its recent success in stabilizing brain tumors suggests it may have a future in oncology. The patient, Lisa Rosendahl, was given only 12 months to live after her brain tumor proved unresponsive to all known treatments. They tested it for cancer and it came back positive," Lisa says. "When I was 21 they found a large mass in my brain and I had it resected right away. Chloroquine brain tumor Our brain tumor cocktails and stories Inhibitors of autophagy, This Malaria Drug Is Having an Amazing Effect on Brain. Hydroxychloroquine remission early onset rheumatoid arthritisPlaquenil dr mercolaGetting a cold while on plaquenilHydroxychloroquine eye screening Glioblastoma multiforme is difficult to treat because the cancer cells develop genetic mutations that cause them to be resistant to treatment, which means that previously effective treatment no longer fights the cancer cells. Chloroquine is a drug that is most often used to treat malaria, an infection that is spread by mosquitoes in some parts of the world. Brain Tumor News Adding Chloroquine to Conventional.. Glioblastoma Treatment Breakthrough 'Untreatable' Brain.. Chloroquine inhibits the malignant phenotype of glioblastoma.. Chloroquine is an antimalaria drug that also suppresses tumor growth and metastasis. Chloroquine neutralizes the pH of intracellular compartments, thereby disrupting the endosomal trafficking and lysosomal function. Whereas chloroquine impairs autophagy and proliferation in tumor cells, Maes et al. found that chloroquine suppressed the growth and metastasis of melanoma by acting on tumor. This medicine may add to the chance of getting some types of cancer. Talk with the doctor. Keep away from children. Accidental exposure may cause death. If a child takes chloroquine by accident, get medical help right away. If you are 65 or older, use chloroquine with care. You could have more side effects. There is a growing evidence that antimalarial chloroquine could be re-purposed for cancer treatment. A dozen of clinical trials have been initiated within the past 10 years to test the potential of chloroquine as an adjuvant treatment for therapy–refractory cancers including glioblastoma, one of the most aggressive human cancers.