Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil for hallux limitus Pool chloroquine tablet Yes, Plaquenil can cause alopecia or hair loss. Plaquenil hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. The Autoimmune Disease the Plaquenil is Used for is Causing Hair loss. Autoimmune disease can cause inflammation in the body and this type of inflammation itself can trigger hair loss in the form of a hair shedding or ‘telogen effluvium.’ When rheumatoid arthritis flares patients can shed hair. When lupus flares, patients can lose hair. Interesting! I had been losing weight fairly rapidly and without trying before starting on Plaquenil - and it stopped after a few weeks of taking it, as did the alarming hair loss. I had no idea Plaquenil could be a weight gain culprit. I've been on Plaq for 4 years now, and weight gain is a problem. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil cause hair loss Plaquenil Hydroxychloroquine Side effects, Images, Uses, Dosage., Hydroxychloroquine Plaquenil and Hair Loss Is my Plaquenil. Quinacrine chloroquine antimalarial Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Plaquenil & Weight Gain/Loss -. Hydroxychloroquine Reviews Everyday Health. Im experienceing the same thing as Allie. I have been on Plaquenil for a year and a half and im losing hair like crazy as well. My Rheumatologist just recently switched my med to Prednisone but i cant really see any changes yet. I believe the Plaquenil does have some kind of affect with hair loss. Many lupus patients suffer from hair loss. Sometimes it's very mild and unnoticeable but for some, it can be quite severe and cause considerable anguish. To help you prevent lupus hair loss, we've put together a list of tips with help from Daily Health. MORE Discover what effect lupus has on. After the first couple months I noticed that my hair was "shedding" a lot. When I brought the concern up to my rheumatologist he said that the hair loss was "probably" due to lupus itself & not the result of taking plaquenil! I found his response strange given the fact that I wasn't losing hair prior to taking plaquenil.