The patient had been treated with hydroxychloroquine for two years prior to presentation. After thorough workup for secondary causes of QT interval prolongation hydroxychloroquine was discontinued and the patient’s QT interval shortened. Why is hydroxychloroquine important in the treatment of lupus Chloroquine suicide What is the chemical name for plaquenil Find information about common, infrequent and rare side effects of Plaquenil Oral. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Cases of long QT syndrome and TdP tachycardia have been described with maprotiline use, but rarely occur when the drug is used alone in normal prescribed doses and in the absence of other known risk factors for QT prolongation. Limited data are available regarding the safety of maprotiline in combination with other QT-prolonging drugs. The patient was noted to have mild prolongation of the QT interval on electrocardiogram prior to initiation of hydroxychloroquine therapy which was exacerbated by its use and may have been caused due to toxicity from underlying renal failure. The patient was treated with mexiletine to prevent sudden ventricular arrhythmias, which was unique compared to other documented cases in which lidocaine was used. Plaquenil and log qt Hydroxychloroquine DermNet NZ, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses How good is plaquenil for diabetesTylenol and hydroxychloroquine Overall 4 patients had a long QTc prior and 8 patients after initiation of HCQ therapy table 1. 8 patients were also taking ≥1 medication known to prolong the QT interval. Conclusion The appreciation of potential drug-induced arrhythmias in Rheumatology patients to date has not been well described. Long QT and Hydroxychloroquine; A Poorly Recognised.. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Oct 15, 2012 CMR may serve as an increasingly important diagnostic modality in antimalarial cardiotoxicity for a number of reasons. Firstly, it is the reference standard for the assessment of LV and RV function and morphology, the latter also commonly abnormal in antimalarial cardiotoxicity. 7,11 –13,17,18 Secondly, CMR also plays a primary role in the exclusion of differential diagnoses. In 2012, the FDA released revised recommendations for citalopram, noting its potential risk for abnormal heart rhythms when prescribed at high doses. 6 Specifically, the FDA advised against citalopram use in patients with congenital long QT syndrome, bradycardia, hypokalemia, hypomagnesemia, recent acute myocardial infarction, or uncompensated. Plaquenil prolongs the QT interval. Ventricular arrhythmias and torsades de pointes have been reported in patients taking Plaquenil see OVERDOSAGE. Therefore, Plaquenil should not be administered with other drugs that have the potential to prolong the QT interval see DRUG INTERACTIONS.