Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and quinine Generic plaquenil shortage Side effects of hydroxychloroquine tablets 200 mg Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. What are some other side effects of Hydroxychloroquine? All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away Dizziness. Headache. Feeling nervous and excitable. Chloroquine has been replaced with hydroxychloroquine as it has less side effects. Eye Exam Before Starting Treatment. If a person is going to be treated long-term with Plaquenil, they need to have a thorough dilated eye exam with best corrected visual acuity, central visual field, color vision, and dilated examination of the retina. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. What are the side effects of the drug hydroxychloroquine Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Hydroxychloroquine Indications, Side Effects. - Silver chloroquineChloroquine phopshate uspSide effects from plaquenil on eye Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Hydroxychloroquine Side Effects and Adverse.. Plaquenil, Plaquenil Sulfate, Quineprox hydroxychloroquine.. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Severe side effects may include allergic reactions. It appears to be safe in pregnancy but this use has not been well studied. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. Side-effects aren't common. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight; feeling sick nausea or indigestion; diarrhoea; headaches; bleaching of the hair or mild hair loss; tinnitus ringing in the ears visual problems.