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The Agency's updated safety information lists difficulty in obtaining an erection that persists indefinitely, even after the discontinuation of finasteride, as a possible side effect of the drug. The UK's Medical and Healthcare Products Regulatory Agency (MHRA) say that erectile dysfunction that persists once use of finasteride has stopped has been reported to them. Similar labeling changes have been made by the Italian government. metformin induced lactic acidosis The first time I came in contact with excellent Canadian director, producer, screenwriter David Cronenberg I was about nine or ten years old (I haven't got a clue how the hell I ended up in front of the TV or who was the responsible parent, hmm...) The film was Rabid and it truly scared the shit out of my tiny intellect. Dan Keloid (Howard Rysphan) gets rabid and freaks out with a pair of scissors during an operation, cutting the nurses finger off, or when he spews some serious rabid fluid when locked inside some kind of asylum ambulance still give me the creeps. I have remained fascinated by Cronenbergs movies over the years, slowly discovering how many different layers they work on (most of them Im probably not aware of at all). At first it was (being a splatter teenager) special effect stuff, the typical horror thrills and the appealing weirdness of it all that interested me. Since then the films have gotten more sophisticated, and so has the horror. I would consider, maybe Dead Ringers (1988) the scariest of Cronenberg's films yet it has nothing to do with the "slasher" genre he so often associated with ("Dave Deprave", "The Baron of Blood"). There's a disturbing feeling over Cronenberg's work. 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